Scientists at South Korea’s Institute for Basic Science (IBS) have developed Nano-MIND, a cutting-edge magnetogenetics technology allowing wireless, remote control of specific brain regions to modulate complex functions such as emotions, social behaviors, and motivation in animals. This breakthrough, detailed in Nature Nanotechnology, uses magnetic fields and magnetized nanoparticles to precisely stimulate targeted brain circuits.
Nano-MIND places nano-magnetoreceptors in specific neurons, enabling activation through rotating magnetic fields at exact times. It demonstrated effectiveness by activating inhibitory GABA receptors in the medial preoptic area, increasing maternal behaviors in non-maternal female mice. Additionally, it regulated feeding behaviors by targeting motivation circuits in the lateral hypothalamus, with activation of inhibitory neurons doubling appetite and activation of excitatory neurons halving it.
This technology offers precise control over neural activity, advancing neuroscience and potential therapeutic applications.
Source – CGTN
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