Chinese researchers have developed a new model that can predict the aging of 13 human organs, including the brain, allowing for more precise assessment of how different organs age. Led by Yang Tielin of Xi’an Jiaotong University, the team identified 119 genetic loci linked to organ aging through genome-wide analysis, showing that most genetic factors are organ-specific rather than shared across the body.
The study also pinpointed 554 genes associated with aging risks in specific organs, helping reveal the key molecular mechanisms behind how each organ ages. According to China Science Daily, the model can accurately assess organ-aging status across different populations and could support early identification of high-risk groups, improve understanding of links between organ aging and chronic diseases, and shed light on how factors like smoking affect the aging of particular organs, paving the way for more targeted prevention and future clinical applications.
Credit : CGTN